Informations sur le produit
2,2,5,6-Tetramethyl-2,3-dihydropyrazine (TMPD) is a chemical compound that inhibits the enzyme that catalyzes the reaction of vitamin K with glutamate to form clotting factors II, VII, IX and X. TMPD is metabolized by rat liver microsomes to 2-amino-4,6-dinitrophenol (DNP). The DNP then reacts with glutathione to produce a toxic product. TMPD has been shown to have anticoagulant effects in rats and is used as an experimental drug for leukemia treatment. TMPD also inhibits microbial growth by acting as a competitive inhibitor of microbial metabolism. This chemical can be found in food items such as caproic acid and has been detected in basophilic leukemia cells.
Propriétés chimiques
Question d’ordre technique sur : 3D-GBA83961 2,2,5,6-Tetramethyl-2,3-dihydropyrazine
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