4,5-Dichloroisothiazole-3-carboxylic acid
CAS : 131947-13-2
Ref. 3D-GFA94713
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| 50mg | Arrêté | ||
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Informations sur le produit
Nom :
4,5-Dichloroisothiazole-3-carboxylic acid
Synonymes :
- 4,5-Dichloro-1,2-Thiazole-3-Carboxylic Acid
Description :
4,5-Dichloroisothiazole-3-carboxylic acid (DCCA) is a cisplatin analog that has been shown to have antiproliferative activity. DCCA binds to the amine group of proteins and forms adducts with a variety of different cells. It has been shown to be cytotoxic to various types of cells in vitro. In vivo, DCCA is metabolized by cytochromes P450 into 4-chloro-5,6-dihydroxyisothiazole, which produces reactive oxygen species that cause apoptotic cell death. DCCA has been shown to have dose-dependent effects on tumor growth in mice when it was administered intraperitoneally and intravenously at concentrations of 25 mg/kg/day and 50 mg/kg/day, respectively.
Avis:
Nos produits sont destinés uniquement à un usage en laboratoire. Pour tout autre usage, veuillez nous contacter.
Marque:
Biosynth
Stockage à long terme :
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Propriétés chimiques
Masse moléculaire :
198.03 g/mol
Formule :
C4HCl2NO2S
Degré de pureté :
Min. 95%
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