4-ethynylpyrimidin-2-amine

CAS : 1207175-18-5

Ref. 3D-HYB17518

Informations sur le produit

• Nom: 4-ethynylpyrimidin-2-amine
• Synonymes: 2-Amino-3-chloro-4-cyano-5-(trifluoromethyl)pyridine, 2-Amino-3-chloro-5-(trifluoromethyl)-isonicotinonitrile, 2-Amino-3-chloro-5-(trifluoromethyl)pyridine-4-carbonitrile, 2-Amino-4-ethynylpyrimidine, 2-Pyrimidinamine, 4-ethynyl-, 4-(2-Phenylethynyl)Pyrimidin-2-Amine, 4-(But-1-Ynyl)Pyrimidin-2-Amine, 4-(Phenylethynyl)pyrimidin-2-amine, 4-(Prop-1-yn-1-yl)pyrimidin-2-amine, 4-(Prop-1-ynyl)pyrimidin-2-amine, 4-ethynyl-2-Pyrimidinamine

Description

Meridianin is a meridianin isolated from the marine sponge Meridion sp. It has been shown to have anti-tumor and anti-inflammatory effects, as well as inhibitory activity on kinases. There are two known analogues of Meridianin, namely 4-ethynylpyrimidin-2-amine and 4,4'-dichloro-6-(4-ethynylpyrimidin-2-amine). The former is an indole alkaloid that has been shown to be an inhibitor of the enzyme histone deacetylase (HDAC), which plays a key role in regulation of gene expression. A nitrosoarene derivative of Meridianin has also been reported to be an inhibitor of kinases.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 123.16 g/mol
• Formule: C₆H₉N₃
• Degré de pureté: Min. 95%