Informations sur le produit
Nom :
A 77-01
Synonymes :
- 4-[3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl]quinoline
- quinoline, 4-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]-
- quinoline, 4-[5-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]-
Description :
A-77-01 is a cytosolic, centroid molecule that has been shown to have antitumor effects. It binds to the tetradentate binding site on lapatinib and inhibits aldehyde oxidase. This inhibition leads to an increase in reactive oxygen species, which can lead to apoptosis and tumor regression. A-77-01 has been shown to bind with nitrogen atoms and fluorescent molecules, such as fluorescein, which are used for techniques such as fluorescence spectrometry. The dihedral angle of this molecule is -90°, making it a nonplanar molecule. The interactions between the tetradentate binding site on lapatinib and the nitrogen atom of A-77-01 are crucial for this drug's activity.
Avis:
Nos produits sont destinés uniquement à un usage en laboratoire. Pour tout autre usage, veuillez nous contacter.
Marque:
Biosynth
Stockage à long terme :
Notes :
Propriétés chimiques
Masse moléculaire :
286.34 g/mol
Formule :
C18H14N4
Degré de pureté :
Min. 95%
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Code SH :
