Informations sur le produit
- N,N'-[1,2-Ethanediylbis[oxy[5-(2-methoxyphenoxy)[2,2'-bipyrimidine]-6,4-diyl]]]bis[4-(1,1-dimethylethyl)benzenesulfonamide]Bosentan dimer1,2-Bis({6-[4-(tert-butyl)phenylsulfonamido]-5-(2-methoxyphenoxy)-[2,2?-bipyrimidin]-4-yl}oxy)ethane
Bosentan impurity C is a stable crystalline compound that is soluble in organic solvents. It has been identified as an impurity of the drug bosentan, and has been found to be present in the drug at concentrations of up to 0.2%. Bosentan impurity C can be prepared by crystallization from an alkaline solution and can also be obtained as a salt form. The salt form is a dimer that consists of two bosentan molecules linked together by one oxygen atom. Bosentan impurity C is stable under normal conditions and does not undergo any changes when exposed to light or heat. This compound has shown no significant adverse effects on humans who have taken it, with no adverse effects on the kidney, liver, or lungs reported.
Propriétés chimiques
Question d’ordre technique sur : 3D-IB64076 Bosentan impurity C
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