3-O-Desethyl-5-O-desmethyl amlodipine

CAS : 1821498-25-2

Ref. 3D-ID153421

Informations sur le produit

• Nom: 3-O-Desethyl-5-O-desmethyl amlodipine

Description

3-O-Desethyl-5-O-desmethyl amlodipine is a drug product that can be used as an analytical reference standard. It is metabolized in vivo to form 5-O-desmethyl amlodipine, which is the active form of this drug. 3-O-Desethyl-5-O-desmethyl amlodipine is also an impurity in the drug product Amlodipine besylate and its CAS number is 1821498-25-2. The synthetic route for this compound starts with the reaction of 2,3,4,6 trichlorobenzeneethanol with sodium hydroxide followed by hydrogenation of the intermediate to yield 3-(2,6 dichlorophenyl) propanoic acid. This acid was then reacted with methylamine to yield 3-(2,6 dichlorophenyl)-N-[(methylamino) methyl]propionamide.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 366.8 g/mol
• Formule: C₁₇H₁₉ClN₂O₅
• Degré de pureté: Min. 95%