13-O-Desmethyl tacrolimus

CAS : 139958-51-3

Ref. 3D-ID161984

Informations sur le produit

• Nom: 13-O-Desmethyl tacrolimus

Description

Tacrolimus is a macrolide immunosuppressant that is used to prevent organ rejection in transplant patients. It binds to the cytosolic protein, FKBP-12, which prevents calcineurin from dephosphorylating and activating nuclear factor of activated T cells (NFAT). Tacrolimus inhibits the production of IL-2 and other cytokines by T cells, suppressing proliferation. Tacrolimus has been shown to be bioequivalent when administered orally or intravenously. Bioavailability may be increased when taken with food.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 789.99 g/mol
• Formule: C₄₃H₆₇NO₁₂
• Degré de pureté: 90%Min
• Couleur/Forme: Powder