Informations sur le produit
- D-prolinamide, L-tyrosyl-L-prolyl-N-methyl-L-phenylalanyl-
- Pl017
PL 017 is a synthetic delta-opioid that binds to kappa opioid receptors and inhibits voltage-dependent calcium channels. It has been shown to be effective in preventing restenosis by inhibiting platelet aggregation, which is the process of blood cells sticking together and forming clots. PL 017 also has an antinociceptive effect, which may be due to its membrane hyperpolarization effect and inhibition of adrenergic receptors. This drug can be used as a diagnostic tool for detecting receptor binding sites in cell cultures.
PL 017 has been shown to inhibit the binding of naloxone, which is an antagonist of opioid receptors, to the mu-opioid receptor by 50%. The molecular modeling technique was used to show that PL 017 binds with high affinity at the delta-opioid receptor site.
Propriétés chimiques
Question d’ordre technique sur : 3D-IDA39756 PL 017
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