Fluticasone propionate EP Impurity F

CAS : 1219174-94-3

Ref. 3D-IF178225

Informations sur le produit

• Nom: Fluticasone propionate EP Impurity F
• Marque: Biosynth
• Description: Fluticasone Propionate EP Impurity F is an impurity of Fluticasone Propionate. Fluticasone Propionate is a synthetic glucocorticoid used in the treatment of asthma and other allergic disorders. Impurity F is a metabolite of Fluticasone Propionate and has been detected in human plasma at low levels (5% of total fluticasone propionate). The metabolism of Fluticasone Propionate to Impurity F has been studied in rat, mouse, dog and man.br>br>The following table summarizes the metabolic pathways that have been identified for this impurity:br>br>Metabolism studies indicate that Impurity F is mainly metabolized by CYP3A4 to form conjugates with glucuronic acid or sulfates. It may also be hydrolyzed to form 5α-flurostan-3β,17β-d

Propriétés chimiques

• Masse moléculaire: 498.56 g/mol
• Formule: C₂₅H₂₉F₃O₅S
• Degré de pureté: Min. 95%
• Couleur/Forme: Powder