Informations sur le produit
- 5-Chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-2,4(1H,3H)-pyrimidinedione
- MA 1 (pharmaceutical)
- TPI (thymidine phosphorylase inhibitor)
- 2,4(1H,3H)-Pyrimidinedione, 5-chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-
Tipiracil is a group P2 epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor that has been shown to have a number of physiological effects in various model organisms. Tipiracil has been shown to be effective against inflammatory bowel disease and colorectal adenocarcinoma, and it can inhibit the proliferation of skin cancer cells in mice. Tipiracil binds to EGFR with high affinity, inhibiting its activation by binding to the ATP-binding site on the tyrosine kinase domain. This prevents autophosphorylation and activation of downstream signaling pathways such as MAPKs, leading to inhibition of cell proliferation. Tipiracil also inhibits DNA synthesis and protein synthesis in cells.
Propriétés chimiques
Question d’ordre technique sur : 3D-IHA20474 Tipiracil
Si vous souhaitez demander un devis ou passer commande, veuillez plutôt ajouter les produits souhaités à votre panier, puis demander un devis ou passer commande à partir de votre panier. C'est une méthode plus rapide, plus économique, et vous pourrez bénéficier des remises disponibles ainsi que d'autres avantages
