S-Methyl-N-cyano-N'-[2-[(5-methyl-1H-imidazol-4-yl)methylthio]ethyl]isothiourea

CAS : 52378-40-2

Ref. 3D-IM58264

Informations sur le produit

• Nom: S-Methyl-N-cyano-N'-[2-[(5-methyl-1H-imidazol-4-yl)methylthio]ethyl]isothiourea
• Synonymes: 2-Cyano-1-methyl-3-[2-[[(5-methylimidazol-4-yl)methyl]thio]ethyl]isothioureaCimetidine impurity AN-Cyano-N'-2-[(5-methyl-1H-imidaz ol-4-yl)methylthio]ethyl-S-methylisothiourea, Carbamimidothioic acid, N-cyano-N′-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]-, methyl ester, Carbamimidothioic acid, N-cyano-N′-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]-, methyl ester, Methyl N-cyano-N′-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]carbamimidothioate, N-Cyano-N'-[2-((4-methyl-5-imidazoly)methylthio)ethyl-S-methylisothiourea, N-Cyano-N'-[2-(4-methyl-5-imidazolyl)methylthio]etheyl-S-methylisothiourea, N-Cyano-N′-[2-[(4-methyl-5-imidazolyl)methylthio]ethyl]-S-methylisothiourea, N-Cyano-N′-[2-[[(5-methyl-4-imidazolyl)methyl]thio]ethyl]-S-methylisothiourea, methyl N-cyano-N'-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)carbamimidothioate

Description

Methylisothiourea is a label that can be used to identify cells in vivo. It is a fluorescent molecule that is activated by the presence of cytokines, such as IL-1β and TNF-α. Methylisothiourea has been used to evaluate corneal epithelial cells for their response to injury. The effect of Methylisothiourea on the tissue was assessed by histology and evaluated by the presence of cytokine concordance with the fluorescence intensity. Reconstitution experiments were conducted in vitro using human tissues. It was found that Methylisothiourea was not toxic at concentrations up to 500 μM and that it did not interfere with DNA synthesis or cell division at concentrations up to 10 mM.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 269.39 g/mol
• Formule: C₁₀H₁₅N₅S₂
• Degré de pureté: Min. 95%
• Couleur/Forme: White Powder
• InChI: InChI=1S/C10H18N4S2/c1-8-9(14-7-13-8)6-16-5-4-12-10(11-2)15-3/h7H,4-6H2,1-3H3,(H,11,12)(H,13,14)
• Code InChI: InChIKey=SFYVXTXBFSMOPB-UHFFFAOYSA-N
• SMILES: CS/C(=N\CCSCc1nc[nH]c1C)NC#N