Triphenylmethanol

CAS : 76-84-6

Ref. 3D-IT28577

Informations sur le produit

• Nom: Triphenylmethanol
• Synonymes: a,a-DiphenylbenzenemethanolZidovudine Impurity DHydroxytriphenylmethaneBL 3756, Bl 3756, Hydroxytriphenylmethane, Methanol, Triphenyl-, Nsc 4050, Trifenilmetanol, Triphenylcarbinol, Triphenylmethyl alcohol, Tritanol, Trityl alcohol, TrtOH, U 45483, α,α-Diphenylbenzenemethanol

Description

Triphenylmethanol (TPM) is an inhibitor of the enzyme alcohol dehydrogenase. It is synthesized by reacting p-hydroxybenzoic acid with a hydroxyl group in the presence of trifluoroacetic acid and potassium carbonate. The reaction solution was then analyzed by x-ray crystallography, revealing the molecular structure of TPM. TPM binds to the metal ion in a hydroxyl group, preventing alcohol dehydrogenase from oxidizing ethanol to acetaldehyde. This mechanism also explains why TPM inhibits other enzymes that use this same metal ion cofactor such as carboxypeptidase A and aminopeptidase P, which are involved in protein synthesis and degradation.

Triphenylmethanol (TPM) is an inhibitor of the enzyme alcohol dehydrogenase. It is synthesized by reacting p-hydroxybenzoic acid with a hydroxyl group in the presence of trif

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 260.33 g/mol
• Formule: C₁₉H₁₆O
• Degré de pureté: Min. 95%
• Couleur/Forme: White Beige Slightly Yellow Powder
• InChI: InChI=1S/C19H16O/c20-19(16-10-4-1-5-11-16,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15,20H
• Code InChI: InChIKey=LZTRCELOJRDYMQ-UHFFFAOYSA-N
• SMILES: OC(c1ccccc1)(c1ccccc1)c1ccccc1