Human glucagon TFA salt

CAS : 9007-92-5

Ref. 3D-JAA00792

Informations sur le produit

• Nom: Human glucagon TFA salt
• Synonymes: Baqsimi, Glucagonoid, Glukagon, HG-Factor, HGF, Hyperglycemic factors, Hyperglycemic-glycogenolytic factor
• CAS: 9007-92-5

Description

Glucagon is a peptide hormone that regulates blood glucose levels. It is synthesized and secreted by alpha cells in the pancreas, and it stimulates the liver to release glucose into the bloodstream. Glucagon TFA salt is a potential drug target for type 2 diabetes. It binds to glucagon receptors on hepatocytes and pancreatic beta-cells, leading to increased insulin secretion, decreased glucagon secretion, increased glycogenolysis, and increased hepatic glucose production. Glucagon TFA salt has high affinity for the glucagon receptor and potent antagonist activity against the receptor. The hydrogen bonds between its hydrophobic side chain and fatty acid groups on the receptor are critical for binding affinity. Glucagon TFA salt has a long half-life of about 3 hours in humans due to its low clearance rate from circulation. This long half-life makes it useful for treating chronic metabolic disorders such as type 2 diabetes mellitus.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 4,052.85 g/mol
• Formule: C₁₅₃H₂₂₅N₄₃O₄₉S•(C₂HF₃O₂)₅
• Degré de pureté: Min. 95%