Vapiprost

CAS : 85505-64-2

Ref. 3D-KDA50564

Informations sur le produit

• Nom: Vapiprost
• Synonymes: (4E)-7-[(1R,2R,3S,5S)-5-(biphenyl-4-ylmethoxy)-3-hydroxy-2-piperidin-1-ylcyclopentyl]hept-4-enoic acid, (4Z)-7-[(1R,2R,3S,5S)-5-([1,1′-Biphenyl]-4-ylmethoxy)-3-hydroxy-2-(1-piperidinyl)cyclopentyl]-4-heptenoic acid, (4Z)-7-[(1R,2R,3S,5S)-5-(biphenyl-4-ylmethoxy)-3-hydroxy-2-piperidin-1-ylcyclopentyl]hept-4-enoic acid, (4Z)-7-[(1R,2R,3S,5S)-5-(biphenyl-4-ylmethoxy)-3-hydroxy-2-piperidin-1-ylcyclopentyl]hept-4-enoic acid hydrochloride, 4-Heptenoic acid, 7-(5-((1,1'-biphenyl)-4-ylmethoxy)-3-hydroxy-2-(1-piperidinyl)cyclopentyl)-, (1R-(1alpha(Z),2beta,3beta,5alpha))-, 4-Heptenoic acid, 7-[(1R,2R,3S,5S)-5-([1,1′-biphenyl]-4-ylmethoxy)-3-hydroxy-2-(1-piperidinyl)cyclopentyl]-, (4Z)-, 4-Heptenoic acid, 7-[5-([1,1′-biphenyl]-4-ylmethoxy)-3-hydroxy-2-(1-piperidinyl)cyclopentyl]-, [1R-[1α(Z),2β,3β,5α]]-, Gr 32191, Gr 322191, Unii-H84Xt1Coau, Vapiprost [INN:BAN], Vapiprostum, Vapiprostum [Latin]

Description

Vapiprost is a peptide inhibitor of the calmodulin-dependent protein kinase II. This enzyme phosphorylates the amino acid residue Thr-286 in the regulatory domain of the protein phosphatase 2A, which causes it to dephosphorylate and activate its substrates. Vapiprost prevents this phosphorylation and activation, thus inhibiting PKII activity. It is not active against other kinases or phosphatases.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 477.60 g/mol
• Formule: C₃₀H₃₉NO₄
• Degré de pureté: Min. 95%