1,5-Anhydro-4,6-O-benzylidene-3-deoxy-D-glucitol

CAS : 152613-20-2

Ref. 3D-MA05144

Informations sur le produit

• Nom: 1,5-Anhydro-4,6-O-benzylidene-3-deoxy-D-glucitol
• Synonymes: 1,5-Anhydro-4,6-O-benzylidene-3-deoxy-D-ribo-hexitol

Description

1,5-Anhydro-4,6-O-benzylidene-3-deoxy-D-glucitol (1,5BPG) is a form compound that is conformationally restricted to the chair conformation. It has inhibitory activity against human macrophages and low activity against thp-1 cells. The 1,5BPG inhibits the activation of Nlrp3 and induces apoptosis in macrophages. These effects are mediated through binding to the hydroxyl group of C2 on the glucose moiety of 1,5BPG. The 1,5BPG also has high activity against marrow derived macrophages. This is due to its ability to inhibit the synthesis of phosphatidic acid and other lipids in these cells.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 236.26 g/mol
• Formule: C₁₃H₁₆O₄
• Degré de pureté: Min. 95%
• Couleur/Forme: Powder