Forodesine

CAS : 209799-67-7

Ref. 3D-MD11591

Informations sur le produit

• Nom: Forodesine
• Synonymes: Immucillin-H, (7-[(2S,3S,4R,5R)-3,4-dihydioxy-5- (hydroxymethyl)-2-pyrrolidinyl]-1,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one), 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 7-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-pyrrolidinyl]-1,5-dihydro-, 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 7-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-pyrrolidinyl]-3,5-dihydro-, 7-[(2S,3S,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-2-pyrrolidinyl]-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, 7-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl]-1,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, 7-[3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl]-1,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one hydrochloride, Fodosine, Ntr 001

Description

Forodesine is a purine nucleoside that inhibits the nucleoside phosphorylase enzyme and prevents the synthesis of purines. It has minimal toxicity and is effective against intracellular targets such as mitochondria, which are important for apoptosis induction. Forodesine also inhibits the mcl-1 protein, which is an inhibitor of t-cell lymphomas. This drug has been shown to be effective in animal models of human lymphoma and leukemia.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 266.25 g/mol
• Formule: C₁₁H₁₄N₄O₄
• Degré de pureté: Min. 95%
• Couleur/Forme: Powder