Ezetimibe b-D-glucuronide

CAS : 190448-57-8

Ref. 3D-ME07193

Informations sur le produit

• Nom: Ezetimibe b-D-glucuronide
• Synonymes: Ezetimibe phenoxy Glucuronide
• Marque: Biosynth
• Description: Ezetimibe b-D-glucuronide is a glucuronide conjugate of ezetimibe. It can be found in human serum, as well as in the liver and small intestine. Ezetimibe b-D-glucuronide has been shown to inhibit uptake of uridine into Caco2 cells, which may be due to its ability to inhibit the activity of drug transporters such as P-glycoprotein and organic anion transporting polypeptides. This drug also inhibits the production of creatine kinase in the liver and lowers cholesterol levels by inhibiting dietary cholesterol absorption. The drug interactions with statins are still unclear and require further investigation. Ezetimibe b-D-glucuronide is metabolized by glucuronidation in the liver and small intestine.

Propriétés chimiques

• Masse moléculaire: 585.55 g/mol
• Formule: C₃₀H₂₉F₂NO₉
• Degré de pureté: Min. 95%
• Couleur/Forme: Powder