Z-VAD-FMK

CAS : 187389-52-2

Ref. 3D-MHA38952

Informations sur le produit

• Nom: Z-VAD-FMK
• Synonymes: 13: PN: WO2005039629 PAGE: 18 claimed protein, 3: PN: WO2011028611 SEQID: 3 unclaimed protein, <span class="text-smallcaps">L</smallcap>-Alaninamide, N-[(phenylmethoxy)carbonyl]-<smallcap>L</span>-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-, L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-, N-[(Benzyloxy)carbonyl]-L-valyl-N-[(3S)-5-fluoro-1-methoxy-1,4-dioxopentan-3-yl]-L-alaninamide, N-[(Phenylmethoxy)Carbonyl]-L-Valyl-N-[(1S)-3-Fluoro-1-(2-Methoxy-2-Oxoethyl)-2-Oxopropyl]-L-Alaninamide, N-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</smallcap>-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-<smallcap>L</span>-alaninamide, Z-VAD(OMe)-FMK, Z-Val-Ala-Asp(OMe)-FMK, z-VAD-FMK

Description

Z-VAD-FMK is a caspase inhibitor that blocks the activation of caspases. It inhibits IL-2 receptor and prevents apoptosis by blocking the nuclear DNA from entering the cell nucleus. Z-VAD-FMK has been shown to inhibit the death of HL60 cells in a model system. It has also been shown to have inhibitory properties against cyclin D2, which is an important factor in the apoptosis pathway. This drug may be used to treat conditions such as leukemia, psoriasis, and arthritis.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 467.49 g/mol
• Formule: C₂₂H₃₀FN₃O₇
• Degré de pureté: Min. 95%