Salicylic acid D-glucuronide

CAS : 7695-70-7

Ref. 3D-MS09950

Informations sur le produit

• Nom: Salicylic acid D-glucuronide
• Synonymes: 2-Carboxyphenyl b-D-glucopyranosiduronic acid, 2-Carboxyphenyl β-D-glucopyranosiduronic acid, Glucopyranosiduronic acid, o-carboxyphenyl, β-D-, β-D-Glucopyranosiduronic acid, o-carboxyphenyl, Salicyl phenolic glucuronide, β-D-Glucopyranosiduronic acid, 2-carboxyphenyl

Description

Salicylic acid D-glucuronide is the major metabolite of aspirin, which is formed by hydrolysis of acetylsalicylic acid. It has been demonstrated to have anti-inflammatory and analgesic effects. Salicylic acid D-glucuronide is excreted in urine and can be detected in human serum. The formation rate of this metabolite varies with the individual's age, sex, and kidney function.
Salicylic acid D-glucuronide can be formed in vitro using hydrochloric acid and acetylsalicylic acid as substrates. This reaction is catalyzed by the enzyme uridine diphosphate glucuronyltransferase (UGT). Salicylic acid D-glucuronide has been shown to form covalent adducts with hydroxyl groups from other molecules in vivo and in vitro, including proteins (e.g., albumin) and DNA bases (e.g.,

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 314.24 g/mol
• Formule: C₁₃H₁₄O₉
• Degré de pureté: Min. 95%
• Couleur/Forme: Powder