8-Bromo-2'-deoxyguanosine

CAS : 13389-03-2

Ref. 3D-NB05782

Informations sur le produit

• Nom: 8-Bromo-2'-deoxyguanosine
• Synonymes: 8-Bromo-2'-deoxy-D-guanosine, 2-amino-8-bromo-9-(2-deoxypentofuranosyl)-3,9-dihydro-6H-purin-6-one, Guanosine, 8-bromo-2′-deoxy-, NSC 105830

Description

8-Bromo-2'-deoxyguanosine is a reactive brominated compound that has been shown to stabilize DNA strands. The effects of 8-bromo-2'-deoxyguanosine on the stability of DNA are due to the steric interactions between the bromine and amines in the DNA backbone, which prevent nucleophilic attack. 8-Bromo-2'-deoxyguanosine is an antihistamine, but it has also been used as a precursor for other drugs such as zidovudine, an antiviral drug used in HIV/AIDS therapy. It has also been proposed as a potential treatment for atherosclerosis.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 346.14 g/mol
• Formule: C₁₀H₁₂BrN₅O₄
• Degré de pureté: Min. 90 Area-%
• Couleur/Forme: Off-White Powder