2-Chloropurine

CAS : 1681-15-8

Ref. 3D-NC15936

Informations sur le produit

• Nom: 2-Chloropurine
• Synonymes: 2-chloro-5H-purine, 2-chloro-7H-purine, 1H-Purine, 2-chloro-, 2-chloro-9H-purine

Description

2-Chloropurine is an organic compound that is a purine analog and a prodrug of 6-mercaptopurine. It has shown to be effective in the treatment of various types of cancer, including leukemia and polycystic ovarian syndrome. 2-Chloropurine is metabolized by hydrolysis to 6-mercaptopurine, which can then be converted into thioguanine nucleotide (TGN) by the action of hydroxide solution. TGN can react with adenine nucleotide to form guanine nucleotide (GMP). 2-Chloropurine has been shown to have anti-inflammatory effects and may be used as a therapeutic agent for inflammatory diseases such as bladder inflammation.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 154.56 g/mol
• Formule: C₅H₃ClN₄
• Degré de pureté: Min. 95%
• Couleur/Forme: White to pale yellow solid.
• InChI: InChI=1S/C5H3ClN4/c6-5-7-1-3-4(10-5)9-2-8-3/h1-2H,(H,7,8,9,10)
• Code InChI: InChIKey=JBMBVWROWJGFMG-UHFFFAOYSA-N
• SMILES: Clc1ncc2[nH]cnc2n1