2'-Deoxy-8-oxoguanosine

CAS : 88847-89-6

Ref. 3D-ND06344

Informations sur le produit

• Nom: 2'-Deoxy-8-oxoguanosine
• Synonymes: 8-Hydroxy-2'-deoxyguanosine8-Oxo-2'-deoxyguanosine8-Oxo-dG2'-Deoxy-8-oxo-D-guanosine, 2'-Deoxy-8-Oxoguanosine, 2′-Deoxy-7,8-dihydro-8-oxoguanosine, 7,8-Dihydro-2'-deoxy-8-oxoguanosine, 7,8-Dihydro-8-oxo-2′-deoxyguanosine, 7,8-Dihydro-8-oxodeoxyguanosine, 8-Hydroxydeoxyguanosine, 8-Oxo-2'-deoxyguanine, 8-Oxo-2′-deoxyguanosine, 8-Oxo-7,8-dihydro-2'-deoxyguanosine, 8-Oxo-7,8-dihydrodeoxyguanosine, 8-Oxo-7-hydrodeoxyguanosine, 8-Oxo-dG, 8-Oxodeoxyguanosine, Ccris 8239, Guanosine, 2'-deoxy-7,8-dihydro-8-oxo-, Guanosine, 7,8-dihydro-2'-deoxy-8-oxo-
• CAS: 88847-89-6

Description

2'-Deoxy-8-oxoguanosine (8-OHdG) is a product of oxidative DNA damage. The presence of 8-OHdG in urine has been used to detect and measure the degree of oxidative DNA damage in humans and animals, which may be linked to cancer and aging. When 8-OHdG is excreted into urine, it can react with other molecules such as protein or inorganic phosphorus, causing more oxidative DNA damage. 2'-Deoxy-8-oxoguanosine has also been shown to cause cell toxicity by damaging the cell's squamous epithelium, leading to cancer.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 283.25 g/mol
• Formule: C₁₀H₁₃N₅O₅
• Degré de pureté: Min. 95 Area-%
• Couleur/Forme: White Powder