1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil

CAS : 144822-63-9

Ref. 3D-ND09139

Informations sur le produit

• Nom: 1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil
• Synonymes: 1-{5-O-[Bis-(4-methoxyphenyl)-phenylmethyl]-2-deoxy-2-fluoro--D-arabinofuranosyl}-2,4(1H,3H)-pyrimidinedione, 1-[(3S,4R,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-3-fluoro-4-hydroxy-tetrahydrofuran-2-yl]pyrimidine-2,4-dione

Description

1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil (1FdUMP) is a synthetic, modified nucleoside that is an antimetabolite. It inhibits DNA synthesis by reacting with the phosphate groups of the deoxyribose sugar, which are needed for DNA synthesis. 1FdUMP is phosphorylated to form 1FdUMP monophosphate and 1FdUMP diphosphate, which are intermediates in DNA synthesis. The phosphoramidites of 1FdUMP can be used to synthesize oligonucleotides for use in research and clinical applications such as anticancer drugs, antiviral agents, or anti-inflammatory agents.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 548.56 g/mol
• Formule: C₃₀H₂₉FN₂O₇
• Degré de pureté: Min. 95%
• Couleur/Forme: White To Off-White Solid