5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine

CAS : 163759-50-0

Ref. 3D-ND36302

Informations sur le produit

• Nom: 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine
• Synonymes: 5'-O-DMT-2'-O-MOE-5-methyluridine, 5'-O-Dmtr- 2'-O-(2-Methoxyethyl)-5-Methyl-Uridine, 5'-O-(Bis(4-Methoxyphenyl)Phenylmethyl)-2'-O-(2-Methoxyethyl)-5-Methyluridine

Description

5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine is a novel, synthetic nucleoside with antiviral and antitumor activity. It is an analogue of 5'-O-DMT-2'-O-(2-methoxyethyl)uridine, which has been shown to be active against herpes simplex virus type 1 (HSV1) in vitro. The phosphoramidites of 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine are modified at the 2' position with a methyl group and at the 5' position with a methoxyethyl group. These modifications make it more resistant to degradation by intracellular enzymes. The anticancer activity of 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine was demonstrated in preclinical studies using human tumor cell lines.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 618.67 g/mol
• Formule: C₃₄H₃₈N₂O₉
• Degré de pureté: Min. 95%
• Couleur/Forme: Off-White Powder