ent-abacavir

CAS : 136470-79-6

Ref. 3D-NE16540

Informations sur le produit

• Nom: ent-abacavir
• Synonymes: (1R,4S)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol(1R-cis)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9 -yl]-2-cyclopentene-1-methanol(1R,4S)-Abacavir, (1R,4S)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol, 2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1R,4S)-

Description

Ent-abacavir is a drug that belongs to the group of antiretroviral drugs. It has minimal toxicity and has been shown to be effective in long-term treatment of HIV/AIDS. Ent-abacavir is also used as part of active antiretroviral therapy, which includes at least three or four different drugs. It inhibits the activity of reverse transcriptase, an enzyme involved in the replication process of HIV and other retroviruses. This drug has been shown to have few drug interactions with other medications, although caution should be taken when using ent-abacavir with drugs that are metabolized by cytochrome P450 enzymes. Ent-abacavir is not recommended for use in patients who have chronic viral hepatitis or who have a body mass index greater than 30 kg/m2 because its pharmacokinetic properties may be altered in these individuals.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 286.33 g/mol
• Formule: C₁₄H₁₈N₆O
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C14H18N6O/c15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21/h1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19)/t8-,10+/m0/s1
• Code InChI: InChIKey=MCGSCOLBFJQGHM-WCBMZHEXSA-N
• SMILES: Nc1nc(NC2CC2)c2ncn([C@@H]3C=C[C@H](CO)C3)c2n1