(-)-Emtricitabine triphosphate sodium salt

CAS : 145819-92-7

Ref. 3D-NE182496

Informations sur le produit

• Nom: (-)-Emtricitabine triphosphate sodium salt
• Synonymes: Triphosphoric acid P-[[(2R,5S)-5-(4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolan-2-yl]methyl] ester sodiumTriphosphoric a cid (2R-cis)-P-[[5-(4-amino-5- fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolan-2-yl]methyl] ester sodium, 5-Fluoro-1-(2-Hydroxymethyl)-1,3-Oxathiolane-5-Yl-Cytidine-5'-Triphosphate, [(2R,5S)-5-(4-amino-5-fluoro-2,6-dioxo-3H-pyrimidin-1-yl)-1,3-oxathiolan-2-yl]methyl-(hydroxy-phosphonooxy-phosphoryl)oxy-phosphinic acid

Description

(-)-Emtricitabine triphosphate sodium salt is a novel antiviral drug that is used to treat HIV/AIDS. It is a deoxyribonucleoside analog of cytidine and is structurally related to lamivudine. It inhibits the synthesis of viral DNA by competitively inhibiting the activity of reverse transcriptase, an enzyme required for this process. Emtricitabine triphosphate sodium salt has been shown to be active against HIV-1, HIV-2, and other strains of human immunodeficiency virus (HIV) in laboratory studies. The drug does not appear to have any effect on normal cells because it does not cross the cell membrane.
Efforts are under way to develop an orally bioavailable form of emtricitabine triphosphate sodium salt as well as new prodrugs with improved properties.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 575.11 g/mol
• Formule: C₈H₉FN₃Na₄O₁₂P₃S
• Degré de pureté: Min. 95%