2-Benzenesulfonamido-5-chlorobenzoic acid
CAS :
Ref. 3D-NFA96458
Informations sur le produit
Nom:2-Benzenesulfonamido-5-chlorobenzoic acid
Marque:Biosynth
Description :2-Benzenesulfonamido-5-chlorobenzoic acid is a potent inhibitor of the enzyme protein tyrosine phosphatase 1B (PTP1B). PTP1B is a negative regulator of insulin signaling and has been found to be associated with type 2 diabetes. This drug binds to the active site of PTP1B and prevents it from dephosphorylating tyrosine residues on the insulin receptor, which activates downstream signaling pathways that lead to glucose uptake.
2-Benzenesulfonamido-5-chlorobenzoic acid has been shown to inhibit tumor cell proliferation in vitro and in vivo. It also inhibits tumor angiogenesis by blocking vascular endothelial growth factor receptor 2 (VEGFR2) signaling.
2-Benzenesulfonamido-5-chlorobenzoic acid has been shown to inhibit tumor cell proliferation in vitro and in vivo. It also inhibits tumor angiogenesis by blocking vascular endothelial growth factor receptor 2 (VEGFR2) signaling.
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Propriétés chimiques
Masse moléculaire :311.74 g/mol
Formule :C13H10ClNO4S
Degré de pureté :Min. 95%