1-Methylpseudouridine

CAS : 13860-38-3

Ref. 3D-NM35520

Informations sur le produit

• Nom: 1-Methylpseudouridine
• Synonymes: 1-Methyl-5-b-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione, (1S)-1,4-anhydro-1-(1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol, 1,4-Anhydro-1-(1-Methyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidin-5-Yl)Pentitol, 1-Methyl-5-β-<span class="text-smallcaps">D</span>-ribofuranosyl-2,4(1H,3H)-pyrimidinedione, 2,4(1H,3H)-Pyrimidinedione, 1-methyl-5-beta-D-ribofuranosyl-, 2,4(1H,3H)-Pyrimidinedione, 1-methyl-5-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, 2: PN: WO2017201317 SEQID: 2 claimed DNA, N¹-Methylpseudouridine, Nsc 240023, U 50228, Uracil, 1-methyl-5-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• CAS: 13860-38-3

Description

1-Methylpseudouridine is a substitute for uridine in modified mRNA. This substitution has shown to increase transfection by reducing immuogenicity. The 1-methylpseudouridine substituted mRNA increases protein expression due to low immune stimulation as it evades detection by the edosomal Toll-like receptor (TLR3).

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 258.23 g/mol
• Formule: C₁₀H₁₄N₂O₆
• Degré de pureté: Min. 95 Area-%
• Couleur/Forme: Powder