2',3',5'-Tri-O-acetyl-8-bromoguanosine

CAS : 15717-45-0

Ref. 3D-NT05775

Informations sur le produit

• Nom: 2',3',5'-Tri-O-acetyl-8-bromoguanosine
• Synonymes: 2',3',5'-Tri-O-acetyl-8-bromo-D-guanosine, 2',3',5'-tri-O-acetyl-8-bromoguanosine, 2-amino-8-bromo-9-(2,3,5-tri-O-acetylpentofuranosyl)-3,9-dihydro-6H-purin-6-one, 2′,3′,5′-Tri-O-acetyl-8-bromoguanosine, 8-Bromo-2′,3′,5′-tri-O-acetylguanosine, 8-Bromoguanosine 2',3',5'-triacetate, 8-Bromoguanosine 2′,3′,5′-triacetate, Guanosine, 8-bromo-, 2′,3′,5′-triacetate, NSC 174056, NSC 79210

Description

2',3',5'-Tri-O-acetyl-8-bromoguanosine is a synthetic nucleoside analog that inhibits the growth of tumor cells. It has been shown to inhibit the progression of prostate cancer and cervical cancer by binding to guanosine, preventing its conversion into ATP. This compound also prevents proliferation in hek293 and glioblastoma cells. The mechanism of action may be due to oxidative phosphite formation, which causes DNA damage and subsequent apoptosis.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 488.25 g/mol
• Formule: C₁₆H₁₈BrN₅O₈
• Degré de pureté: Min. 95%
• Couleur/Forme: Off-White To Light (Or Pale) Yellow Solid