β-Cyclodextrin polymer crosslinked with epichlorohydrin

Ref. 3D-OC33935

Informations sur le produit

• Nom: β-Cyclodextrin polymer crosslinked with epichlorohydrin
• Synonymes: Poly-beta-cyclodextrin (Cross-linked by Epichlorohydrin)
• Marque: Biosynth
• Description: β-Cyclodextrin polymer crosslinked with epichlorohydrin (β-CD-EP) is a high molecular weight, water-insoluble compound that combines the advantageous properties of cyclodextrins and polymers. It is synthesized by crosslinking β-cyclodextrin molecules with epichlorohydrin (either the R- or S-isomer, although is normally a racemic mixture) under strongly alkaline conditions. This material retains the host-guest complex formation ability of cyclodextrins while offering enhanced stability and physicochemical properties. In pharmaceuticals, β-CD-EP serves as an effective drug carrier, improving the solubility and bioavailability of poorly water-soluble drugs, masking unpleasant tastes, and enabling controlled release of active ingredients. Its insoluble nature makes it particularly useful in environmental applications for removing organic pollutants and heavy metals from water. In analytical chemistry, β-CD-EP is employed for the extraction and concentration of target substances, such as mycotoxins from beverages. The polymer's unique structure, featuring a dense, hydrophobic cross-linked core and a more hydrophilic surface, contributes to its dual adsorption mechanism through the inclusion of complex formation and physical adsorption. Recent advancements have led to β-CD-EP variants with ionic functional groups, expanding its potential in water treatment and pharmaceutical formulations.

Propriétés chimiques

• Couleur/Forme: Powder