Informations sur le produit
- Solasodamine
- (3beta,22alpha,25R)-spirosol-5-en-3-yl 6-deoxy-alpha-L-mannopyranosyl-(1->2)-[beta-D-glucopyranosyl-(1->3)]-beta-D-galactopyranoside
- (3beta,22alpha,25S)-spirosol-5-en-3-yl 6-deoxy-alpha-L-mannopyranosyl-(1->2)-[beta-D-glucopyranosyl-(1->3)]-beta-D-galactopyranoside
- (3beta,22alpha,25S)-spirosol-5-en-3-yl 6-deoxyhexopyranosyl-(1->2)-[hexopyranosyl-(1->3)]hexopyranoside
- (3β,22α,25R)-Spirosol-5-en-3-yl O-6-deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl-(1→2)-O-[β-<smallcap>D</smallcap>-glucopyranosyl-(1→3)]-β-<smallcap>D</span>-galactopyranoside
- Nsc 82149
- Solasonin
- Spirosolane, β-<span class="text-smallcaps">D</span>-galactopyranoside deriv.
- Tomatine solaradixine
- alpha-Solasonine
- Voir d'autres synonymes
- beta-D-Galactopyranoside, (3beta,22alpha,25R)-spirosol-5-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-2)-O-(beta-D-glucopyranosyl-(1-3))-
- α-Solasonine
- β-<span class="text-smallcaps">D</smallcap>-Galactopyranoside, (3β,22α,25R)-spirosol-5-en-3-yl O-6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→2)-O-[β-<smallcap>D</span>-glucopyranosyl-(1→3)]-
Solasonine is a cytotoxic glycoalkaloid found in plants of the genus Solanum. This steroidal glucoside has anti-proliferative activity and can trigger apoptosis. In breast cancer cell lines, it activates the mitochondrial cytochrome c-mediated pathway. In a liver cancer in vitro model, solasonine inhibits interactions between mortalin, a Hsp70 chaperone, and tumor suppressor p53, allowing p53 to activate the cell death pathway.
Propriétés chimiques
Question d’ordre technique sur : 3D-OS65589 Solasonine
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