2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N6-phenoxyacetyladenosine 3'-CE phosphoramidite

Ref. 3D-PB08940

Informations sur le produit

• Nom: 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N6-phenoxyacetyladenosine 3'-CE phosphoramidite
• Synonymes: 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N6-phenoxyacetyl-D-adenosine 3'-CE phosphoramiditePac-A-CE Phosphoramidite

Description

2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N6-phenoxyacetyladenosine 3'-CE phosphoramidite is a nucleoside analogue that is synthesized by the condensation of 5'-O-DMT-N6-phenoxyacetyladenosine and 2'-deoxyadenosine. It has antiviral, anticancer and immunomodulatory properties. This compound is novel and modified in that it contains a silyl group at the 2' position, which renders the molecule inactive as an inhibitor of human thymidine kinase.
2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N6-phenoxyacetyladenosine 3'-CE phosphoramidite inhibits viral replication by interfering with DNA synthesis. It also has been shown to inhibit tumor cell proliferation and promote apoptosis in vitro

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 1,018.25 g/mol
• Formule: C₅₄H₆₈N₇O₉PSi
• Degré de pureté: Min. 95%
• Couleur/Forme: Powder