Big Endothelin-1 (Rat, 1-39)

Ref. 3D-PED-4266-S

Informations sur le produit

• Nom: Big Endothelin-1 (Rat, 1-39)
• Synonymes: Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-Val-Asn-Thr-Pro-Glu-Arg- Val-Val-Pro-Tyr-Gly-Leu -Gly-Ser-Pro-Ser-Arg-Ser
• Marque: Biosynth
• Description: This product has disulfide bonds between Cys1-Cys15 and Cys3-Cys11, is courced from: Rat, 1-39 and is available as a 0.1mg vial. Big Endothelin-1 (Rat, 1-39) is a precursor peptide of the vasoconstrictor Endothelin-1 (ET-1). ET-1 exhibits vasoconstrictive properties and is an activator of endothelin G-protein coupled receptors. Furthermore ET-1 is produced when inflammation, vascular stress or hypoxia occurs. In vivo Big Endothelin-1 has a greater half life compared to ET-1 and therefore makes it useful to study secretory activity in the endothelial system.Overall Big Endothelin-1 (Rat, 1-39) can be used as a research tool for studying protein interactions, receptor activation and function, and ligand binding. This peptide is also used in pharmacology to study the effects of therapeutic agents on receptor activity and expression.

Propriétés chimiques

• Masse moléculaire: 4,389 g/mol
• Formule: C₁₉₂H₂₉₂N₅₀O₅₈S₅
• Degré de pureté: Min. 95%