NY-ESO-1 (123-137) DRB1*04:01

Ref. 3D-PP51086

Informations sur le produit

• Nom: NY-ESO-1 (123-137) DRB1*04:01
• Synonymes: H-LKEFTVSGNILTIRL-OH

Description

NY-ESO-1 protein:
NY-ESO-1 (123-137) DRB1*04:01 is an epitope analogue of the New York esophageal squamous cell carcinoma-1, also named cancer testis. NY-ESO-1 is expressed in 82% of neuroblastomas and 46% of melanomas but also in many others solid tumors and hematological malignancies. That’s why, NY-ESO-1 peptides are attractive targets for specific immunotherapies and for the stimulation of human NY-ESO-1 specific CD8+ T cells.
Applications of NY-ESO-1 (123-137) DRB1*04:01:
Results of studies suggest after stimulation of NY-ESO-1 (123-137) DRB1*04:01 specific T cells and IFN- ELISPOT and chronium release assays that NY-ESO-1 (123-137) DRB1*04:01 can be an immunogenic epitope encoded by NY-ESO-1. NY-ESO-1 (123-137) DRB1*04:01 contains epitope capable of binding HLA-DR molecules.

• Marque: Biosynth