Informations sur le produit
- Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr- Ala-NH2
- Parathyroid Hormone Related Protein
- PTH-rP 1-34 (Human
- rat
- mouse) amide
- Pth-Rp (Human, 1-34 Amide) (Rat, Mouse)
- Parathyroid Hormone Related Protein (Human, 1-34 Amide) (Rat, Mouse)
- Hypercalcemia Of Malignancy Factor*Fragm Ent 1-34 Am
- Parathyroid hormone-related protein (1-34) Amide, PTHrP (1-34) amide, Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-NH2
PTH-rP is a peptide that belongs to the group of activators. PTH-rP has been shown to activate phospholipase C, which leads to increased intracellular calcium levels and activation of protein kinase C. PTH-rP also binds to the receptor for parathyroid hormone (PTH), and activates it by binding to its extracellular domain. This receptor is found in most cells in the body, including those in bone, kidney, gut and brain. The ligand-receptor interaction causes an increase in intracellular calcium levels that triggers a cascade of downstream effects on cell metabolism and gene expression.
Propriétés chimiques
Question d’ordre technique sur : 3D-PTH-4205-V PTH-rP (Human,1-34 Amide)
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