Phosphonic acid, methylenebis-, tetramethyl ester
CAS : 16001-93-7
Ref. 3D-RAA00193
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Informations sur le produit
- Methylenediphosphonic acid tetramethyl ester
- Tetramethyl Methanediylbis(Phosphonate)
Methylenebisphosphonic acid is a phosphonic acid with an inhibitory effect on enzymes. It has been shown to have strong inhibitory properties against gram-negative bacteria and inhibits the growth of Mycobacterium tuberculosis. Methylenebisphosphonic acid also inhibits the production of cytokines, such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β), by inflammatory cells, which may contribute to its anti-inflammatory properties. Methylenebisphosphonic acid also blocks apoptotic cell death by inhibiting the activation of caspase 3, an enzyme that cleaves other proteins involved in apoptosis. Methylenebisphosphonic acid binds to Ca2+ response proteins and blocks their ability to regulate cellular processes. This prevents the release of cytochrome C from mitochondria, which initiates a cascade of reactions leading to cell death.
Propriétés chimiques
Question d’ordre technique sur : 3D-RAA00193 Phosphonic acid, methylenebis-, tetramethyl ester
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