3D-RYB71580 - amiodarone-d4-hydrochloride-solution | 1216715-80-8
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Desethylamiodarone Hydrochloride 1.0 mg/ml in Methanol (as free base)
CAS :Couleur et forme :Single SolutionDesethylamiodarone (2-Butyl-3-benzofuranyl-4-[2-(ethylamino)ethoxy]-3,5-diiodophenyl Ketone Hydrochloride)
CAS :Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoiFormule :C23H25I2NO3·HClCouleur et forme :White Off-White SolidMasse moléculaire :652.96907Desethyl Amiodarone Hydrochloride
CAS :Formule :C23H26ClI2NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :653.7194Amiodarone EP Impurity B HCl (N-Desethyl Amiodarone HCl)
CAS :Formule :C23H25I2NO3·HClCouleur et forme :White To Off-White SolidMasse moléculaire :617.27 36.46Desethylamiodarone hydrochloride
CAS :Desethylamiodarone HCl, CYP3A product, antiarrhythmic inhibiting K+ channels, IC50 19.1 μM, main amiodarone metabolite.Formule :C23H26ClI2NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :653.72Amiodarone EP Impurity B (as Hydrochloride)
CAS :Produit contrôléFormule :C23H25I2NO3·ClHCouleur et forme :NeatMasse moléculaire :653.72Desethyl Amiodarone Hydrochloride
CAS :Impurity Amiodarone EP Impurity B / Amiodarone USP Related Compound B
Applications Desethyl Amiodarone Hydrochloride (Amiodarone EP Impurity B) is a metabolite of Amiodarone, a non-selective ion channel blocker.
References Ha, H., et al.: Eur. J. Clin. Pharmacol., 55, 807 (2000), Arai, K., et al.: J. Biochem., 132, 529 (2002), Carson, B., et al.: J. Med. Chem., 31, 623 (2002),Formule :C23H25I2NO3·ClHCouleur et forme :Off-WhiteMasse moléculaire :653.72Desethyl amiodarone hydrochloride
CAS :Amiodarone hydrochloride is an antiarrhythmic drug that belongs to the class of chromatographic agents. It is a prodrug, which is metabolized to amiodarone in vivo. Amiodarone has been shown to be effective in preventing ventricular fibrillation and malignant arrhythmias. Amiodarone prevents the onset of cardiac arrhythmia by prolonging the action potential duration and refractory period, which stabilizes the cell membrane potential during depolarization. The drug also inhibits the release of calcium ions from the sarcoplasmic reticulum, thereby reducing excitability and preventing re-entry into a fibrillating state. Amiodarone is used for the treatment of atrial fibrillation, ventricular tachycardia, and chronic heart failure.Formule :C23H25I2NO3•HClDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :653.72 g/mol
