16β-Hydroxytestosterone

CAS : 17528-90-4

Ref. 3D-SAA52890

Informations sur le produit

• Nom: 16β-Hydroxytestosterone
• Synonymes: 4-androsten-16-beta 17-beta-diol-3-one, Androst-4-En-3-One, 16,17-Dihydroxy-, (16Beta,17Beta)-

Description

16β-Hydroxytestosterone is a synthetic androgen that is developed as a male contraceptive. The drug was reconstituted to be injected into the rat liver microsomes, which are the primary site of metabolism. 16β-Hydroxytestosterone inhibits the activities of NADPH-cytochrome P450 reductase (CPR) and cytochrome P450 enzymes, including CYP2D6, CYP3A4, CYP2C19, and CYP1A2. It also inhibits the activity of monoclonal antibodies that bind to CPR. In this study, 16β-hydroxytestosterone has been shown to inhibit the activity of p450 isozymes in Sprague-Dawley rats without affecting other enzyme activities. 16β-Hydroxytestosterone can be used for the treatment of prostate cancer or for contraception in males. This drug should not be used with nitrates or other drugs containing nitric oxide because

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 304.4 g/mol
• Formule: C₁₉H₂₈O₃
• Degré de pureté: Min. 95%
• Couleur/Forme: Powder