TBK1/IKKµ-IN-2

CAS : 1292310-49-6

Ref. 3D-SBC31049

Informations sur le produit

• Nom: TBK1/IKKµ-IN-2
• CAS: 1292310-49-6

Description

BMS-345541 is a selective inhibitor of TBK1/IKKµ-IN-2, a protein complex that plays an important role in the inflammatory response. It inhibits the phosphorylation of IκBα and IKKβ (inhibitors of NF-κB), thereby suppressing the activation of NF-κB and its downstream inflammatory cytokines. BMS-345541 has been shown to inhibit proinflammatory cytokine production in vitro and in vivo in animals. The drug interacts with both catalytic subunits of TBK1/IKKµ-IN-2, suggesting that it may be used as a potential therapeutic agent for inflammatory conditions such as rheumatoid arthritis or Crohn's disease.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 457.52 g/mol
• Formule: C₂₆H₂₇N₅O₃
• Degré de pureté: Min. 95%