Saredutant

CAS : 142001-63-6

Ref. 3D-SFA00163

Informations sur le produit

• Nom: Saredutant
• Synonymes: Benzamide, N-[(2S)-4-[4-(acetylamino)-4-phenyl-1-piperidinyl]-2-(3,4-dichlorophenyl)butyl]-N-methyl-, Benzamide, N-[4-[4-(acetylamino)-4-phenyl-1-piperidinyl]-2-(3,4-dichlorophenyl)butyl]-N-methyl-, (S)-, N-[(2S)-4-[4-(Acetylamino)-4-phenyl-1-piperidinyl]-2-(3,4-dichlorophenyl)butyl]-N-methylbenzamide, N-[(2S)-4-[4-(acetylamino)-4-phenylpiperidin-1-yl]-2-(3,4-dichlorophenyl)butyl]-N-methylbenzamide, Sr 48968, Sr 48968C

Description

Saredutant is a potent, selective, and orally bioavailable antagonist of the glucocorticoid receptor. This drug has been approved for the treatment of IBD (inflammatory bowel disease) in Japan. Saredutant has also been shown to be effective for treating cancer and bowel disorders that are induced by inflammation. Saredutant is a potent anti-inflammatory agent that inhibits neutrophil infiltration into the inflamed bowel mucosa and reduces mucosal edema. It also inhibits CD4+ T cells from producing proinflammatory cytokines such as IL-2, IFN-γ, and TNF-α. Saredutant has been shown to reduce systolic blood pressure in animal studies, suggesting that it may have antihypertensive effects.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 552.5 g/mol
• Formule: C₃₁H₃₅Cl₂N₃O₂
• Degré de pureté: Min. 95%