Dilmapimod

CAS : 444606-18-2

Ref. 3D-USA60618

Informations sur le produit

• Nom: Dilmapimod
• Synonymes: 8-(2,6-Difluorophenyl)-4-(4-fluoro-2-methylphenyl)-2-[(2-hydroxy-1-hydroxymethylethyl)amino]-8H-pyrido[2,3-d]pyrimidin-7-one, Pyrido[2,3-d]pyrimidin-7(8H)-one, 8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-2-[[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-, 8-(2,6-Difluorophenyl)-4-(4-fluoro-2-methylphenyl)-2-[[2-hydroxy-1-(hydroxymethyl)ethyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one, SB 681323

Description

Dilmapimod is an inhibitor of the enzyme phosphatidylinositol-3-kinase (PI3K) that is involved in the signaling pathway that leads to the release of proinflammatory cytokines. It has been shown to inhibit the production of high-sensitivity C-reactive protein, leukemia inhibitory factor, and interleukin-6, a potent inflammatory mediator. This drug also inhibits the proliferation of pluripotent cells and induces differentiation into cells with a more limited potential. Dilmapimod has been used as a diagnostic tool for identifying patients with autoimmune diseases who have increased levels of high sensitivity c-reactive protein. The drug inhibits tumor necrosis factor alpha (TNFα), which plays a role in chronic inflammation and cancer progression.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 456.42 g/mol
• Formule: C₂₃H₁₉F₃N₄O₃
• Degré de pureté: Min. 95%