Lucidenic acid B

CAS : 95311-95-8

Ref. 3D-VDA31195

Informations sur le produit

• Nom: Lucidenic acid B
• Synonymes: (+)-Lucidenic acid B, (5α,7β,12β)-7,12-Dihydroxy-4,4,14-trimethyl-3,11,15-trioxochol-8-en-24-oic acid, Chol-8-en-24-oic acid, 7,12-dihydroxy-4,4,14-trimethyl-3,11,15-trioxo-, (5α,7β,12β)-

Description

Lucidenic acid B is a molecule that has been shown to have cytotoxic effects on human HL-60 cells. It also has the ability to reduce the glomerular filtration rate, which may be due to its ability to inhibit the synthesis of growth factors and mitochondrial membrane potential. Lucidenic acid B also inhibits cancer cell proliferation, as it induces apoptosis. In addition, this molecule has been shown to inhibit cyclooxygenase-2 (COX-2) activity, which leads to an inhibition of prostaglandin synthesis and subsequent prostaglandin-mediated inflammation. Lucidenic acid B also specifically binds to NF-κB DNA binding sites and inhibits nuclear translocation of NF-κB subunits p65 and p50.

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 474.59 g/mol
• Formule: C₂₇H₃₈O₇
• Degré de pureté: Min. 95%