Informations sur le produit
- 4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(2R,3S)-2-(hydroxymethyl)-1-methyl-3-pyrrolidinyl]-, hydrochloride (1:1)
- P 276-00
P276-00 is an inhibitor of the MCL-1 protein, which is a pro-apoptotic protein. It has been shown to inhibit polymerase chain reaction (PCR) amplification of DNA in hl-60 cells and miapaca-2 cells. P276-00 is also active against cancer cells that have acquired drug resistance through the activation of MCL-1. This inhibitor blocks the kinase activity associated with MCL-1 and has been shown to be effective in treating bowel diseases, urinary infections, and cancer.