L 454560

CAS : 346629-30-9

Ref. 3D-WNA62930

Informations sur le produit

• Nom: L 454560

Description

L 454560 is a ligand that binds to the phosphodiesterases PDE2B, PDE3A, and PDE5A. It is under investigation for the treatment of cognitive dysfunction associated with cardiovascular diseases. L 454560 has been shown to be effective in improving memory retention in preclinical models. In addition, it inhibits platelet aggregation in vitro and improves blood flow in vivo.

L 454560 has been shown to have a pharmacokinetic profile that is linear and dose proportional, with detectable levels at low doses (1-10 mg/kg). There are no significant drug-drug interactions observed between L 454560 and other drugs. The drug target for L 454560 is the phosphodiesterase enzyme family which regulates biochemical reactions involved in cognition and cardiovascular function.

Ligands such as L 454560 can be developed into potential drugs by targeting specific enzymes or proteins involved in disease pathology via inhibition or activation of these enzymes

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 587.7 g/mol
• Formule: C₃₁H₂₉N₃O₅S₂
• Degré de pureté: Min. 95%