Alpinumisoflavone

CAS : 34086-50-5

Ref. 3D-XA161646

Informations sur le produit

• Nom: Alpinumisoflavone
• Synonymes: 2H,6H-Benzo[1,2-b:5,4-b']dipyran-6-one, 5-hydroxy-7-(p-hydroxyphenyl)-2,2-dimethyl-(8CI)5-Hydroxy-7-(4-hydroxyphenyl)-2,2-dimethyl- 2H,6H-benzo[1,2-b:5,4-b']dipyran-6-one, 2H,6H-Benzo[1,2-b:5,4-b′]dipyran-6-one, 5-hydroxy-7-(p-hydroxyphenyl)-2,2-dimethyl-, 2H,6H-benzo[1,2-b:5,4-b']dipyran-6-one, 5-hydroxy-7-(4-hydroxyphenyl)-2,2-dimethyl-, 5-Hydroxy-7-(4-hydroxyphenyl)-2,2-dimethyl-2H,6H-benzo[1,2-b:5,4-b′]dipyran-6-one, Alpinum-iso-flavone
• CAS: 34086-50-5

Description

Alpinumisoflavone is a natural compound found in the plant Alpinia officinarum. It has shown significant cytotoxicity against human osteosarcoma cells. Alpinumisoflavone has been shown to induce apoptosis of HL-60 cells through activation of caspase-3 and cleavage of poly (ADP-ribose) polymerase. It also inhibits the proliferation of L1210 leukemia cells and induces cell cycle arrest at G2/M phase. The biological effects of alpinumisoflavone are mediated by the toll like receptor 4 (TLR4) and its downstream signaling pathways, including NF-κB, MAPK, and PI3K/Akt.
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• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 336.34 g/mol
• Formule: C₂₀H₁₆O₅
• Degré de pureté: Min. 95%
• Couleur/Forme: White Powder