Informations sur le produit
Odorine is a flavonoid derivative that has been shown to have an inhibitory effect on the growth of cancer cells. It also inhibits the production of prostaglandin E2 and thromboxane A2, which are substances that stimulate cell proliferation. Odorine has been shown to be cytotoxic in vivo, inhibiting the development of skin papillomas in mice. The molecular docking analysis has revealed that the interaction between odourine and the receptor protein is mainly through hydrophobic interactions at the interface of Phe-521 and Trp-527. This interaction may lead to significant anticancer activity.
The chemical structures of odourine are shown below:
Odorine can be synthesized by reacting an acetylenic diol with a mixture of phenylboronic acid and pyridine in acetic acid. This reaction produces two products: odorine and hydrogen cyanide (HCN). Odorine can also be
