Xanthohumol D

CAS : 274675-25-1

Ref. 3D-XX178046

Informations sur le produit

• Nom: Xanthohumol D
• Synonymes: 1-[2,4-Dihydroxy-3-(2-hydroxy-3-methyl-3-buten-1-yl)-6-methoxyphenyl]-3-(4 hydroxyphenyl)-2-propen-1-one, 1-[2,4-Dihydroxy-3-(2-hydroxy-3-methyl-3-butenyl)-6-methoxyphenyl]-3-(4 hydroxyphenyl)-2-propen-1-one, 2-Propen-1-one,1-[2,4-dihydroxy-3-(2-hydroxy-3-methyl-3-butenyl)-6-methoxyphenyl]-3-(4-hydroxyphenyl)-,(2E)-

Description

Xanthohumol D is a flavonoid derivative that is structurally related to prenylflavonoids. It has been shown to have an inhibitory effect on the enzyme cyclooxygenase-2 (COX-2) and as such, has been suggested as a potential cancer drug. Xanthohumol D also inhibits the growth of cancer cells by inhibiting protein synthesis, which may be due to its structural similarity with other potent COX-2 inhibitors. This compound also has the ability to enhance the effects of chemotherapeutic agents. Xanthohumol D is not very soluble in water and it is only slightly soluble in ethanol. A 1% solution of xanthohumol D in methanol can be prepared by adding 0.1g of xanthohumol D to 100 mL methanol and shaking for 30 minutes at room temperature. In addition, this compound has an nmr spectrum that can be used for its

• Marque: Biosynth

Propriétés chimiques

• Masse moléculaire: 370.14164
• Formule: C₂₁H₂₂O₆
• Degré de pureté: Min. 95%
• InChI: InChI=1S/C21H22O6/c1-12(2)17(24)10-15-18(25)11-19(27-3)20(21(15)26)16(23)9-6-13-4-7-14(22)8-5-13/h4-9,11,17,22,24-26H,1,10H2,2-3H3/b9-6+
• Code InChI: InChIKey=IIWLGOCXDBSFCM-RMKNXTFCSA-N
• SMILES: C=C(C)C(O)Cc1c(O)cc(OC)c(C(=O)/C=C/c2ccc(O)cc2)c1O