Informations sur le produit
06:0-12:0 NBD pg is an artificial fluorescent probe for studying protein interactions and receptor pharmacology. It selectively binds to the extracellular loops of a ligand-gated ion channel, such as nicotinic acetylcholine receptors (nAChRs) and glycine receptors. The fluorescence of 06:0-12:0 NBD pg is quenched by the binding of its ligands to the receptor, indicating that this probe can be used to monitor the conformational changes in these receptors.
06:0-12:0 NBD pg has been used to study nAChRs and glycine receptors in cultured cells and intact animals. In these studies, 06:0-12:0 NBD pg was used as a tool for examining ligand binding kinetics, affinity, and selectivity.
This probe is also useful for studying protein interactions with peptides or antibodies. When 06:0-12:0
