Hispidulin

CAS : 1447-88-7

Ref. BP-BP0730

Informations sur le produit

• Nom: Hispidulin
• Synonymes: Methoxyapigenin, 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-, 4′,5,7-Trihydroxy-6-methoxyflavone, 5,7,4′-Trihydroxy-6-methoxyflavone, 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one, 6-Methoxy-5,7,4′-trihydroxyflavone, 6-Methoxyapigenin, 6-Methylscutellarein, 6-O-Methylscutellarein, Dinatin, Flavone, 4′,5,7-trihydroxy-6-methoxy-, Hispedulin, Hispiludin, NSC 122415, Salvitin, Scutellarein 6-Methyl Ether

Description

Hispidulin has anti-oxidative, anti-inflammatory, anti-cancer, antiepileptic, neuroprotective, anti-osteoporotic and bone resorption attenuating effects, it targets the VEGF receptor 2-mediated PI3K/Akt/mTOR signaling pathway in endothelial cells, leading to the suppression of pancreatic tumor growth and angiogenesis. Hispidulin can ameliorate high glucose-mediated endothelial dysfunction via inhibiting PKCβII-associated NLRP3 inflammasome activation and NF-κB signaling, it has potential application in the prevention and treatment of diabetic vascular complications. Hispidulin can inhibit platelet aggregation by elevating cAMP levels by a mechanism different from that of theophylline or PGE1.

• Marque: Biopurify

Propriétés chimiques

• Masse moléculaire: 300.266
• Formule: C₁₆H₁₂O₆
• Degré de pureté: 95%~99%
• InChI: InChI=1S/C16H12O6/c1-21-16-11(19)7-13-14(15(16)20)10(18)6-12(22-13)8-2-4-9(17)5-3-8/h2-7,17,19-20H,1H3
• Code InChI: InChIKey=IHFBPDAQLQOCBX-UHFFFAOYSA-N
• SMILES: COc1c(O)cc2oc(-c3ccc(O)cc3)cc(=O)c2c1O