DR6 (phospho-Ser562) rabbit pAb

Ref. EK-ES16898

Informations sur le produit

• Nom: DR6 (phospho-Ser562) rabbit pAb
• Synonymes: Tumor necrosis factor receptor superfamily member 21 (Death receptor 6) (CD antigen CD358)

Description

This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq, Jul 2013],

• Marque: ELK Biotechnology